New weekly shot aims for major, Long-Term weight loss

NCT ID NCT06780449

Summary

This study is testing a new weekly injection called CagriSema to see if it helps people with obesity lose weight and keep it off long-term. About 400 adults will receive either the real medicine or a placebo (dummy medicine) for two years, followed by a one-year extension phase. Researchers will measure weight loss, health improvements, and safety over the full three years.

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Contacts and locations

Locations

  • APDP - Associação Protectora dos Diabéticos de Portugal

    Lisbon, 1250-189, Portugal

  • Aarhus Universitetshospital, Steno Diabetes Center Aarhus

    Aarhus, 8200, Denmark

  • Addenbrooke's Hospital_Cambridge

    Cambridge, CB2 0QQ, United Kingdom

  • Aintree University Hospital

    Liverpool, L9 7AL, United Kingdom

  • Alpha Recherche Clinique - Lebourgneuf

    Québec, G2J 0C4, Canada

  • CHU Helora - Hôpital de Mons - Site Constantinople

    Mons, 7000, Belgium

  • CUF Descobertas

    Lisbon, 1998-018, Portugal

  • Cliniques Universitaires Saint-Luc - Serv Endocrinologie - Diabétologie

    Brussels, 1200, Belgium

  • Diablo Clinical Research, Inc.

    Walnut Creek, California, 94598, United States

  • Dr. M.B. Jones Inc

    Victoria, British Columbia, V8V 4A1, Canada

  • East West Medical Research Institute_Honolulu

    Honolulu, Hawaii, 96814, United States

  • Gentofte Hospital - Center for Klinisk Metabolisk Forskning

    Hellerup, 2900, Denmark

  • Holston Medical Group_Bristol

    Bristol, Tennessee, 37620, United States

  • Hospital Cuf Descobertas S.A.

    Lisbon, 1998-018, Portugal

  • Hospital Luz Arrabida, S.A.

    Vila Nova de Gaia, 4400-346, Portugal

  • Hvidovre Hospital Endokrinologisk forsknings afsnit 159

    Hvidovre, 2650, Denmark

  • Joint Clinical Research Facility - Swansea

    Swansea, SA2 8PP, United Kingdom

  • L-MARC Research Center

    Louisville, Kentucky, 40213, United States

  • Musgrove Park Hospital

    Taunton, TA1 5DA, United Kingdom

  • North Texas Endocrine Center

    Dallas, Texas, 75231, United States

  • Nova Scotia Health Authority

    Halifax, Nova Scotia, B3H 2Y9, Canada

  • Premier Clinical Trial Research Network (PCTRN)

    Hamilton, Ontario, L8L 5G4, Canada

  • Royal London Hospital - Blizard Institute

    London, E1 2AJ, United Kingdom

  • Sjællands Universitetshospital, Køge - Medicinsk Afdeling

    Køge, 4600, Denmark

  • Southmead Hospital

    Bristol, BS10 5NB, United Kingdom

  • Spartanburg Medical Research

    Spartanburg, South Carolina, 29303, United States

  • StudyMetrix Research LLC

    City of Saint Peters, Missouri, 63303, United States

  • Sydvestjysk Sygehus Esbjerg - Medicinsk Endokrinologisk Ambulatorium, Forskningsenheden

    Esbjerg, 6700, Denmark

  • ULS De Matosinhos E.P.E.- Hospital Pedro Hispano

    Senhora Da Hora, Matosinhos, Matosinhos, 4464-513, Portugal

  • UZ Leuven - Endocrinology

    Leuven, 3000, Belgium

  • UZA - UZ Antwerpen - Department of Endocrinology

    Edegem, 2650, Belgium

  • Unidade Local de Saude de Sao Joao E.P.E

    Porto, 4200-319, Portugal

  • University Hospital Coventry - WISDEM Centre

    Coventry, CV2 2DX, United Kingdom

  • Valley Clinical Trials

    Covina, California, 91723, United States

  • Washington Cntr Weight Mgmt

    Arlington, Virginia, 22206, United States

  • Yale University School Of Medicine

    New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.