New combo therapy targets Hard-to-Treat prostate cancer

NCT ID NCT05613894

First seen Oct 31, 2025 · Last updated Jun 11, 2026 · Updated 27 times

Summary

This study tests a combination of two drugs—cabozantinib (a targeted therapy) and 177Lu-PSMA-617 (a radioactive drug)—in men with advanced prostate cancer that no longer responds to hormone therapy. The goal is to find the safest dose and see if the combination can slow cancer growth. About 33 participants will take part in this early-phase trial.

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Contacts and locations

Locations

  • Huntsman Cancer Institute at University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.