New drug shows promise in calming opioid withdrawal

NCT ID NCT04470050

Completed Symptom relief Sponsor: BioXcel Therapeutics Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This study tested a new medicine called BXCL501 to see if it can safely reduce the unpleasant symptoms people feel when they stop taking opioids. 225 adults with opioid use disorder took part. The medicine was given as a film under the tongue, and researchers measured withdrawal symptoms using standard scales. The goal was to find out if BXCL501 can make withdrawal more manageable.

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Conditions

The condition(s) this trial relates to.

morphine dependence opiate dependence Psychomotor Agitation substance withdrawal syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID WITHDRAWAL

Contacts and locations

Locations

BioXcel Clinical Research Site

Miami Lakes, Florida, 33016, United States
BioXcel Clinical Research Site

Marlton, New Jersey, 08053, United States
BioXcel Clinical Research Site

New York, New York, 10032, United States

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