New drug aims to shield kidneys from heart surgery harm

NCT ID NCT07164833

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests a drug called BX-001N to see if it can prevent acute kidney injury in people having heart surgery. About 40 adults will receive either a low dose, high dose, or a placebo. The goal is to see if the drug can keep kidneys working well after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BX-001N

What this could lead to

If it works, this could lead to a new way to prevent kidney damage after heart surgery, reducing the risk of long-term kidney problems.

What could go wrong

This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. The drug may not prove effective or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury aortic disorder ischemia reperfusion injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Keimyung University Dongsan Medical Center

    NOT_YET_RECRUITING

    Daegu, 42601, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Korea University Anam Hospital

    RECRUITING

    Seoul, 02841, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pusan National University Yangsan Hospital

    RECRUITING

    Yangsan, 50612, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Samsung Medical Center

    NOT_YET_RECRUITING

    Seoul, 06351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Seoul Asan Medical center

    RECRUITING

    Seoul, 05505, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Seoul National University Bundang Hospital

    NOT_YET_RECRUITING

    Seongnam, 13620, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Severance Hospital

    RECRUITING

    Seoul, 03722, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••