New drug aims to shield kidneys from heart surgery harm

NCT ID NCT07164833

Recruiting now Prevention Sponsor: Bilix Co.,Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests a drug called BX-001N to see if it can prevent acute kidney injury in people having heart surgery. About 40 adults will receive either a low dose, high dose, or a placebo. The goal is to see if the drug can keep kidneys working well after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BX-001N
What this could lead to: If it works, this could lead to a new way to prevent kidney damage after heart surgery, reducing the risk of long-term kidney problems.
What could go wrong: This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. The drug may not prove effective or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic disorder ischemia reperfusion injury acute kidney injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SURGERY ASSOCIATED - ACUTE KIDNEY INJURY ISCHEMIA REPERFUSION INJURY

Contacts and locations

Locations

Keimyung University Dongsan Medical Center
NOT_YET_RECRUITING

Daegu, 42601, South Korea
Korea University Anam Hospital
RECRUITING

Seoul, 02841, South Korea
Pusan National University Yangsan Hospital
RECRUITING

Yangsan, 50612, South Korea
Samsung Medical Center
NOT_YET_RECRUITING

Seoul, 06351, South Korea
Seoul Asan Medical center
RECRUITING

Seoul, 05505, South Korea
Seoul National University Bundang Hospital
NOT_YET_RECRUITING

Seongnam, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Severance Hospital
RECRUITING

Seoul, 03722, South Korea

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