New study seeks best remedy for chronic mouth burning

NCT ID NCT06040190

First seen Jun 24, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This study compares four treatments—clonazepam, capsaicin, photobiomodulation (light therapy), and alpha-lipoic acid—against a placebo for burning mouth syndrome. Researchers will enroll 150 adults with daily oral burning for over 3 months. The goal is to see which approach best reduces pain and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
clonazepam, capsaicin, photobiomodulation, alpha-lipoic acid
What this could lead to
If successful, this trial could identify which treatment best reduces burning mouth pain and improves daily life.
What could go wrong
This is a small, early-phase study with no guarantee that any treatment will work better than placebo. Results may not apply to everyone with burning mouth syndrome.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Federal university of minas gerais

    Belo Horizonte, Minas Gerais, Brazil

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