New dissolving stent could improve heart artery treatment

NCT ID NCT03168776

Completed Disease control Sponsor: Sino Medical Sciences Technology Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tested a new type of stent (a small mesh tube) that slowly dissolves after being placed in a heart artery. The stent is coated with a drug to prevent the artery from narrowing again. Over 1600 patients with stable heart disease or a mild heart attack received either the new stent or a standard permanent stent. Researchers tracked heart-related deaths, heart attacks, and the need for repeat procedures for up to 5 years to see if the new stent is safer and works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BuMA Supreme biodegradable drug-coated coronary stent

What this could lead to

If successful, this could provide a safer, more effective option for opening blocked heart arteries, potentially reducing long-term complications.

What could go wrong

This is a completed trial comparing two stents, so results are known. However, the new stent may not prove superior to existing ones, and any stent carries risks like blood clots or re-narrowing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

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Locations

Amsterdam UMC

Amsterdam, Netherlands
AnMed Health

Anderson, South Carolina, 29621, United States
Aultman Hospital

Canton, Ohio, 44710, United States
Berks Cardiologists, Ltd.

Wyomissing, Pennsylvania, 19610, United States
Bethesda Hospital East/Daniel Heart and Vascular Center

Boynton Beach, Florida, 33435, United States
CHI Health Research Center

Omaha, Nebraska, 68124, United States
CHU Charleroi

Charleroi, Belgium
Cardiology, PC

Birmingham, Alabama, 35211, United States
Cardiovascular Associates of Delaware Valley

Haddon Heights, New Jersey, 08035, United States
Cardiovascular Institute of Northwest Florida

Panama City, Florida, 32401, United States
Clearwater Cardiovascular Consultants

Clearwater, Florida, 33756, United States
Columbia University Medical Center / New York Presbyterian Hospital

New York, New York, 10032, United States
Dignity Health - Mercy Gilbert Medical Center / Chandler Regional Medical Center

Gilbert, Arizona, 85297, United States
Doylestown Hospital

Doylestown, Pennsylvania, 18901, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Essential Health

Duluth, Minnesota, 55805, United States
Florida Hospital Tampa

Tampa, Florida, 33613, United States
Foothills Medical Centre

Calgary, Alberta, T2N-2T9, Canada
Geisinger Clinic

Danville, Pennsylvania, 17822, United States
Genesis Hospital

Zanesville, Ohio, 43701, United States
Hospital Clinic de Barcelona

Barcelona, Spain
Hospital Ramon y Cajal

Madrid, Spain
Hospital Universitari de Bellvitge

Barcelona, Spain
Hospital Álvaro Cunqueiro

Vigo, 36312, Spain
Imelda

Bonheiden, 2820, Belgium
Inselspital, Universitätsspital Bern

Bern, 3010, Switzerland
Instituto de Investigación Hospital 12 de Octubre

Madrid, Spain
Iowa Heart Center

Des Moines, Iowa, 50314, United States
Jessa Hospital

Hasselt, 3500, Belgium
Kettering Medical Center

Kettering, Ohio, 45429, United States
Krannert Institute of Cardiology

Indianapolis, Indiana, 46202, United States
Lindner Research Center

Cincinnati, Ohio, 45219, United States
MCL

Leeuwarden, Netherlands
Maasstad Ziekenhuis

Rotterdam, Netherlands
MediQuest Research Group Inc.

Ocala, Florida, 34471, United States
Medstar Union Memorial Hospital

Baltimore, Maryland, 21218, United States
Medstar Washington HWospital Center

Washington D.C., District of Columbia, 20010, United States
Mercy St. Vincent Medical Center

Toledo, Ohio, 43608, United States
Michigan Heart

Ypsilanti, Michigan, 48197, United States
NC Heart and Vascular Research

Raleigh, North Carolina, 27607, United States
North MS Medical Center

Tupelo, Mississippi, 38801, United States
North Ohio Heart

Elyria, Ohio, 44035, United States
Northern Michigan Hospital d.b.a. McLaren Northern Michigan

Petoskey, Michigan, 49770, United States
Norton Brownsboro Hospital

Louisville, Kentucky, 40241, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
Shonan Kamakura General Hospital

Kanagawa, Kamakura City, 247-8533, Japan
Smidt Heart Institute Cedars-Sinai Maedical Center

Los Angeles, California, 90048, United States
St Bartholomew's Hospital

London, United Kingdom
St. Michael's Hospital

Toronto, Ontario, M5B-1W8, Canada
St. Vincent's Medical Group

Indianapolis, Indiana, 46290, United States
Swedish Medical Center

Seattle, Washington, 98122, United States
Tyler Cardiovascular Consultants

Tyler, Texas, 75701, United States
University Hospital Geneva HUG, Clinic for Cardiology

Geneva, 1211, Switzerland
University of Virginia Health System

Charlottesville, Virginia, 22908, United States
William Beaumont Hospital

Royal Oak, Michigan, 48073, United States
Winchester Medical Center

Winchester, Virginia, 22601, United States
Yale University

New Haven, Connecticut, 06520, United States
Ziekenhuis Oost Limburg Genk

Genk, 3600, Belgium