Injection or sling? new trial aims to settle the best fix for leakage

NCT ID NCT06480227

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 22 times

Summary

This study compares two treatments for stress urinary incontinence (leaking urine with cough, sneeze, or exercise) in 358 women who haven't gotten enough relief from conservative care. One group gets a bulking agent injection into the urethra (up to two injections over 12 months), and the other gets a single-incision sling surgery. The main goal is to see which approach makes more women feel "much better" or "very much better" after one year.

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Contacts and locations

Locations

  • Brown/ Women and Infants Hospital of Rhode Island, Division of Urogynecology and Reconstructive Pelvic Surgery

    RECRUITING

    Providence, Rhode Island, 02903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Duke University, Duke Division of Urogynecology and Reconstructive Pelvic Surgery

    RECRUITING

    Durham, North Carolina, 27707, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kaiser Permanente -- San Diego

    RECRUITING

    San Diego, California, 92110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California at San Diego

    RECRUITING

    La Jolla, California, 92037-0974, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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