Scientists hunt for clues to BTK drug resistance in leukemia

NCT ID NCT07099443

First seen Dec 16, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study collects blood, bone marrow, or lymph node samples from 60 people with chronic lymphocytic leukemia (CLL) who are taking or about to take BTK degraders. Researchers will analyze the samples to find out why some patients stop responding to these drugs. The goal is to better understand resistance and develop smarter treatments in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Régional Universitaire de Nancy

    NOT_YET_RECRUITING

    Nancy, France

    Contact Email: •••••@•••••

  • CHD Vendée

    NOT_YET_RECRUITING

    La Roche-sur-Yon, France

    Contact Email: •••••@•••••

  • CHU de Angers

    NOT_YET_RECRUITING

    Angers, France

    Contact Email: •••••@•••••

  • CHU de Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, France

    Contact Email: •••••@•••••

  • CHU de Clermont-Ferrand

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

    Contact Email: •••••@•••••

  • CHU de Montpellier

    NOT_YET_RECRUITING

    Montpellier, France

    Contact Email: •••••@•••••

  • CHU de Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

    Contact Email: •••••@•••••

  • Centre Henri-Becquerel de Rouen

    NOT_YET_RECRUITING

    Rouen, France

    Contact Email: •••••@•••••

  • Centre Léon Bernard

    NOT_YET_RECRUITING

    Lyon, France

    Contact Email: •••••@•••••

  • Hôpital Avicenne (AP-HP)

    NOT_YET_RECRUITING

    Paris, France

    Contact Email: •••••@•••••

  • Hôpital Universitaire Pitié Salpêtrière de Paris

    NOT_YET_RECRUITING

    Paris, France

    Contact Email: •••••@•••••

  • Institut Bergonié

    NOT_YET_RECRUITING

    Bordeaux, France

    Contact Email: •••••@•••••

  • Institut Paoli-Calmettes (Marseille)

    NOT_YET_RECRUITING

    Marseille, France

    Contact Email: •••••@•••••

  • University Hospital

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.