New hope for brittle bones: major trial tests drug to shield kids from fractures

NCT ID NCT05972551

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This study aims to see if a new drug called romosozumab works better than standard medications at preventing broken bones in children and teens with osteogenesis imperfecta (brittle bone disease). About 106 participants, aged 5 to 18, will receive either the new drug or standard treatment for a year. Researchers will compare how many fractures occur in each group and measure changes in bone strength.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Boston Childrens Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Centermed Krakow Sp zoo
RECRUITING

Krakow, 31-530, Poland
Centre Hospitalier Universitaire Sainte Justine
RECRUITING

Montreal, Quebec, H3T 1C5, Canada
Centre Hospitalier Universitaire Vaudois
RECRUITING

Lausanne, 1011, Switzerland
Centre Hospitalier Universitaire de Bordeaux - Hopital Pellegrin
RECRUITING

Bordeaux, 33076, France
Centro Ricerche Cliniche Di Verona Societa responsabilita limitata
RECRUITING

Verona, 37134, Italy
Centrum Medyczne Medyk Spolka z Ograniczona Odpowiedzialnoscia Spolka Komandytowa
RECRUITING

Rzeszów, 35-326, Poland
Childrens Hospital of Alabama
RECRUITING

Birmingham, Alabama, 35233, United States
Childrens Hospital of Eastern Ontario
RECRUITING

Ottawa, Ontario, K1H 8L1, Canada
Childrens Hospital of Soochow University
RECRUITING

Suzhou, Jiangsu, 215000, China
Ege Universitesi Tip Fakultesi Hastanesi
RECRUITING

Izmir, 35100, Turkey (Türkiye)
Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
Gazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi
RECRUITING

Ankara, 06500, Turkey (Türkiye)
Gillette Childrens Hospital and Clinic Saint Paul
RECRUITING

Saint Paul, Minnesota, 55101, United States
Hopital Necker Enfants Malades
RECRUITING

Paris, 75743, France
Hospital Sant Joan de Deu
RECRUITING

Esplugues de Llobregat, Catalonia, 08950, Spain
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitari i Politecnic La Fe
RECRUITING

Valencia, Valencia, 46026, Spain
Hospital Universitario Infantil Niño Jesus
RECRUITING

Madrid, 28009, Spain
Hospital Universitario de Getafe
RECRUITING

Getafe, Madrid, 28905, Spain
Hospital de Cruces
RECRUITING

Barakaldo, Basque Country, 48903, Spain
IRCCS Istituto Giannina Gaslini
RECRUITING

Genova, 16147, Italy
Indiana University
RECRUITING

Indianapolis, Indiana, 46202, United States
Instytut Centrum Zdrowia Matki Polki
RECRUITING

Lodz, 93-338, Poland
Karadeniz Teknik Universitesi Tip Fakultesi
RECRUITING

Trabzon, 61080, Turkey (Türkiye)
Kennedy Krieger Institute
RECRUITING

Baltimore, Maryland, 21287, United States
Kepler Universitaetsklinikum GmbH
RECRUITING

Linz, 4020, Austria
Marmara Universitesi Tip Fakultesi Hastanesi
RECRUITING

Istanbul, 34890, Turkey (Türkiye)
Marshfield Clinic
RECRUITING

Marshfield, Wisconsin, 54449, United States
Mayo Clinic Childrens Center
TERMINATED

Rochester, Minnesota, 55905, United States
Monash Childrens Hospital
RECRUITING

Clayton, Victoria, 3168, Australia
Narodny ustav detskych chorob
RECRUITING

Bratislava, 833 40, Slovakia
National Center for Child Health and Development
RECRUITING

Setagaya-ku, Tokyo, 157-8535, Japan
Nemours Childrens Hospital
RECRUITING

Orlando, Florida, 32827, United States
Nemours Hospital for Children
RECRUITING

Wilmington, Delaware, 19803, United States
Okayama Saiseikai Outpatient Center Hospital
RECRUITING

Okayama, Okayama-ken, 700-0013, Japan
Okayama University Hospital
RECRUITING

Okayama, Okayama-ken, 700-8558, Japan
Osaka Womens and Childrens Hospital
RECRUITING

Izumi-shi, Osaka, 594-1101, Japan
Peking Union Medical College Hospital
RECRUITING

Beijing, Beijing Municipality, 100730, China
Perth Childrens Hospital
RECRUITING

Nedlands, Western Australia, 6909, Australia
Phoenix Childrens Hospital
RECRUITING

Phoenix, Arizona, 85016, United States
Queen Elizabeth University Hospital
RECRUITING

Glasgow, G51 4TF, United Kingdom
Royal Manchester Childrens Hospital
RECRUITING

Manchester, M13 9WL, United Kingdom
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Centralny Szpital Kliniczny UMeds
RECRUITING

Lodz, 91-738, Poland
Semmelweis Egyetem
RECRUITING

Budapest, 1094, Hungary
Shandong Provincial Hospital
RECRUITING

Jinan, Shandong, 250021, China
Shanghai Sixth Peoples Hospital
RECRUITING

Shanghai, 200233, China
Sheffield Childrens Hospital
RECRUITING

Sheffield, S10 2TH, United Kingdom
Szpital Miejski w Tychach Spolka z ograniczona odpowiedzialnoscia
RECRUITING

Tychy, 43-100, Poland
The First Bethune Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130021, China
The Hospital for Sick Children
RECRUITING

Toronto, Ontario, M5G 1X8, Canada
The University of Hong Kong-Shenzhen Hospital
RECRUITING

Shenzhen, Guangdong, 518053, China
Tongji Hospital , Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430030, China
Universitaets-Kinderspital beider Basel
RECRUITING

Basel, 4031, Switzerland
Universitaetsklinikum Koeln
RECRUITING

Cologne, 50937, Germany
Universitaetsklinikum Wuerzburg
RECRUITING

Würzburg, 97074, Germany
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
RECRUITING

Leuven, 3000, Belgium
University of California, Los Angeles Interventional Clinical Trials
RECRUITING

Los Angeles, California, 90095, United States
University of South Florida - Carol and Frank Morsani Center for Advanced Health Care
RECRUITING

Tampa, Florida, 33606, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37212-3157, United States
West China Hospital Sichuan University
RECRUITING

Chengdu, Sichuan, 610044, China

Conditions

Explore the condition pages connected to this study.

OSTEOGENESIS IMPERFECTA