New 'Bridging' method could soften smile lines with less filler

NCT ID NCT07178119

Recruiting now Symptom relief Sponsor: Dr. Joseph M Novoa Libermann Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new way to inject hyaluronic acid filler for nasolabial folds (smile lines). Instead of filling the fold directly, the 'Bridging Technique' places tiny horizontal threads of filler under the skin to lift and soften the line. 60 adults aged 30–65 will receive the treatment and be followed for 6 months to see if it improves appearance and is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hyaluronic acid dermal filler (AILEENE Vol. 2)
What this could lead to: If it works, this could offer a more natural-looking way to soften smile lines with less filler and fewer side effects.
What could go wrong: This is a small, early study with no control group, so results may not apply to everyone. Risks include bruising, swelling, or uneven results, as with any filler.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FACIAL AGING NASOLABIAL FOLD CORRECTION SKIN REJUVENATION WRINKLES SUCH AS NASOLABIAL FOLDS

Contacts and locations

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Locations

JNL Aesthetics Limited
RECRUITING

Warrington, Cheshire, WA4 1DQ, United Kingdom

Contact Email: •••••@•••••

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