New trial hopes to stop lung transplant failure before it starts

NCT ID NCT07410312

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tests whether adding the anti-inflammatory drug Anakinra to the solution that donor lungs are stored in can prevent primary graft dysfunction — a serious complication after lung transplant that causes low oxygen and lung inflammation. The study will enroll 20 lung transplant recipients and measure outcomes like graft function on day 3, ICU stay, and hospital stay. It is not yet recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Anakinra (a drug that blocks inflammation)

What this could lead to

If it works, this could reduce the risk of severe lung injury right after transplant, potentially improving recovery and shortening hospital stays.

What could go wrong

This is a very early, small trial (20 people) testing a new use for an existing drug. It may not show clear benefit, and results may not apply to all transplant patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University

    Chicago, Illinois, 60611, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••