Spinal stimulation and special air may help spinal injury patients breathe easier

NCT ID NCT07135583

Recruiting now Disease control Sponsor: Thomas Jefferson University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two non-invasive techniques to improve breathing in people with chronic spinal cord injury. Participants will receive spinal cord stimulation and breathe special air mixtures to strengthen breathing muscles. The study involves 20 adults with incomplete spinal cord injuries and aims to find biomarkers that predict who benefits most.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcutaneous spinal cord stimulation and hypercapnic-hypoxia (special air mixtures)
What this could lead to: If successful, this could lead to a new non-invasive therapy that improves breathing and reduces lung infection risk in people with chronic spinal cord injury.
What could go wrong: This is a small early-phase study with only 20 participants, so results may not apply to everyone. The techniques are experimental and may not produce lasting improvements.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INCOMPLETE SPINAL CORD INJURY SPINAL CORD INJURY CERVICAL SPINAL CORD INJURY THORACIC SPINAL CORD INJURY, CHRONIC

Contacts and locations

Locations

Thomas Jefferson University Center City Campus
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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