Same position, sharper picture: new method aims to line up breast scans
NCT ID NCT07883460
First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time
Summary
PET/CT and MRI scans of the breast are usually taken with the patient in different body positions, which can shift the breast's shape and make it hard to compare findings. This study tests whether scanning women with breast cancer in a dedicated prone breast position during PET/CT can reduce those differences. Participants, who are already scheduled for PET/CT and PET/MRI as part of their care, receive an extra low-dose CT and an additional PET acquisition using the tracer already given. Researchers then develop and evaluate image registration methods to align the scans and measure how accurately findings transfer between them.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- prone breast PET/CT imaging with a dedicated positioning setup
- What this could lead to
- If it works, doctors could match PET/CT and MRI findings more precisely, which may improve how breast cancer is assessed and tracked.
- What could go wrong
- This is a small imaging study with 20 participants, so the method may not work as well in routine practice. The extra scans add a few minutes of lying still and a small amount of radiation from the low-dose CT.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female sex * Clinically indicated PET/CT and PET/MRI of the breast * Histologically confirmed breast cancer Exclusion Criteria: * Age under 18 years * Pregnancy * Lack of capacity to provide informed consent * Possible conception within the previous 14 days * Inability to remain still in the prone position for approximately 10 minutes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Nuclear Medicine, University Hospital Münster
Münster, North Rhine-Westphalia, 48149, Germany
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