Could AI and ultrasound replace unnecessary breast biopsies?

NCT ID NCT06171607

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether contrast-enhanced ultrasound (CEUS) combined with machine learning can more accurately tell if a breast mass is benign or malignant. 100 women with suspicious breast masses will receive CEUS with a contrast agent. The goal is to see if this approach can reduce the need for invasive biopsies by correctly identifying benign masses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Contrast-enhanced ultrasound with perflutren lipid microspheres or sulfur hexafluoride lipid microspheres

What this could lead to

If successful, this could provide a more accurate, non-invasive way to diagnose breast masses, potentially sparing many women from unnecessary biopsies.

What could go wrong

This is an early Phase 1 study with only 100 participants, so results may not apply to all patients. The machine learning model may not perform as well in real-world settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast carcinoma breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Los Angeles County-USC Medical Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • USC / Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••