Early trial tests new vaccine combo to train immune system against aggressive breast cancer

NCT ID NCT02826434

Summary

This early-stage study is testing a new vaccine (PVX-410) alone and combined with an immunotherapy drug (durvalumab) for women who have already finished standard treatment for stage II or III triple-negative breast cancer. The main goals are to check if the treatments are safe and to see if they can trigger the patient's own immune system to recognize and attack any remaining cancer cells. It is a small, initial study to gather safety and early response data.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33607, United States

  • Massachusetts general Hospital

    Boston, Massachusetts, 02114, United States

  • New York University School of Medicine

    New York, New York, 10016, United States

Conditions

Explore the condition pages connected to this study.