New drug combo tested to shrink aggressive breast cancer before surgery

NCT ID NCT04230109

Summary

This study is testing whether the drug sacituzumab govitecan, alone or combined with pembrolizumab, can shrink tumors before surgery in people with localized triple-negative breast cancer. About 260 participants will receive the study treatment for up to 12 weeks, followed by standard chemotherapy if needed. Researchers want to see if this approach can eliminate cancer from the breast and lymph nodes and improve surgery options.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-••••

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-••••

    Contact

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Massachusetts General Hospital - North Shore Cancer Center

    RECRUITING

    Danvers, Massachusetts, 01923, United States

    Contact Phone: •••-•••-••••

    Contact

  • Massachusetts General Hospital at Newton-Wellesley Hospital

    RECRUITING

    Newton, Massachusetts, 02462, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.