New hope for advanced breast cancer patients after standard treatment fails

NCT ID NCT06982521

Recruiting now Disease control Sponsor: Relay Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This global Phase 3 trial is testing which of two drug combinations works better to control advanced breast cancer that has a specific genetic change (PIK3CA mutation) and has worsened after standard hormone therapy. It will enroll about 540 adults whose cancer has returned or spread. The main goal is to see which combination keeps the cancer from growing longer and is safer for patients.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AOU Ferrara, Arcispedale Sant'Anna
RECRUITING

Cona, 44124, Italy
Aalborg University Hospital
RECRUITING

Aalborg, Denmark
Avera Cancer Institute
RECRUITING

Sioux Falls, South Dakota, 57105, United States
Azienda Ospedaliera Universitaria Careggi
RECRUITING

Florence, 50134, Italy
Ballarat Oncology & Haematology Service
RECRUITING

Wendouree, Victoria, 3355, Australia
Banner MD Anderson Cancer Center
RECRUITING

Gilbert, Arizona, 85234, United States
Barwon Health
RECRUITING

Geelong, Victoria, 3220, Australia
Baylor Scott and White Research Institute
RECRUITING

Temple, Texas, 76508, United States
Beverly Hills Cancer Center
RECRUITING

Beverly Hills, California, 90211, United States
CEON+ Pesquisas
RECRUITING

São Caetano do Sul, São Paulo, 09541-270, Brazil
CHU-UCL Namur, Site Sainte-Elisabeth
RECRUITING

Namur, Belgium
Cancer Care Centers of Brevard
RECRUITING

Palm Bay, Florida, 32909, United States
Cancer Center of Kansas
RECRUITING

Wichita, Kansas, 67214, United States
Cedars-Sinai Medical Center
RECRUITING

Beverly Hills, California, 90211, United States
Centre Leon Berard
RECRUITING

Lyon, 69008, France
City of Hope
RECRUITING

Duarte, California, 91010, United States
Clinica Universidad de Navarra
RECRUITING

Madrid, 28027, Spain
Columbia University Herbert Irving Medical Center
RECRUITING

New York, New York, 10032, United States
Community Health Network
RECRUITING

Indianapolis, Indiana, 46250, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Florida Cancer Specialists
RECRUITING

Fort Myers, Florida, 33901, United States
Hong Kong United Oncology Centre
RECRUITING

Hong Kong, HGK, Hong Kong
Hospital Beata Maria Ana/IOB Madrid
RECRUITING

Madrid, 28007, Spain
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Juan Ramon Jimenez
RECRUITING

Huelva, 21005, Spain
Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States
Huntsman Cancer Center, University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States
Irmandade da Santa Casa de Misericórdia de Porto Alegre
RECRUITING

Porto Alegre, 90020-090, Brazil
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
John Theurer Cancer Center at Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center
RECRUITING

Baltimore, Maryland, 21287, United States
Medical Oncology Hematology Consultants
RECRUITING

Newark, Delaware, 19713, United States
Medical University of Graz
RECRUITING

Graz, 8010, Austria
Medstar Georgetown University Hospital
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Memorial Sloan-Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Minnesota Oncology Hematology
RECRUITING

Minneapolis, Minnesota, 55404, United States
Mount Sinai
RECRUITING

New York, New York, 10029, United States
NOB (Nucleo de Oncologia da Bahia)
RECRUITING

Salvador, 40170-110, Brazil
NYU Langone Cancer Center
RECRUITING

New York, New York, 10016, United States
Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68130, United States
Oregon Health & Science University
RECRUITING

Portland, Oregon, 97210, United States
Profound Research LLC
RECRUITING

Royal Oak, Michigan, 48073, United States
Radboud UMC
RECRUITING

Nijmegen, 6525, Netherlands
Renown Regional Medical Center
RECRUITING

Reno, Nevada, 89502, United States
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Rocky Mountain Cancer Centers
RECRUITING

Longmont, Colorado, 80504, United States
Rush Medical College
RECRUITING

Chicago, Illinois, 60607, United States
Rutgers Cancer Institute
RECRUITING

New Brunswick, New Jersey, 08901, United States
Seoul National University Bundang Hospital
RECRUITING

Seoul, 13620, South Korea
Stanford University School of Medicine
RECRUITING

Palo Alto, California, 94304, United States
Studienzentrale für das MVZ Eggenfelden GbR
RECRUITING

Eggenfelden, 84307, Germany
Sunshine Hospital
RECRUITING

Saint Albans, Victoria, 3021, Australia
Sydney Adventist Hospital
RECRUITING

Wahroonga, New South Wales, 2076, Australia
Sygehus Sønderjylland
RECRUITING

Sønderborg, Denmark
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Tennessee Cancer Specialists
RECRUITING

Knoxville, Tennessee, 37909, United States
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States
Texas Oncology Central/South
RECRUITING

Austin, Texas, 78745, United States
Texas Oncology DFW
RECRUITING

Dallas, Texas, 75246, United States
UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
University of California Davis
RECRUITING

Sacramento, California, 95817, United States
University of California San Diego
RECRUITING

San Diego, California, 92037, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Kansas Medical Center
RECRUITING

Westwood, Kansas, 66205, United States
University of Michigan Comprehensive Cancer Center
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Mississippi Medical Center
RECRUITING

Jackson, Mississippi, 39213, United States
University of Texas M.D. Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
University of Wisconsin
RECRUITING

Madison, Wisconsin, 53792, United States
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States
Virginia Oncology Associates
RECRUITING

Norfolk, Virginia, 23502, United States
Vitaz, Campus Sint-Niklaas
RECRUITING

Sint-Niklaas, Belgium
Washington University
RECRUITING

St Louis, Missouri, 63110, United States
William Osler Health System- Brampton Civic Hospital
RECRUITING

Brampton, Ontario, L6R 3J7, Canada
Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED BREAST CANCER BREAST CANCER HER2-NEGATIVE BREAST CANCER HORMONE RECEPTOR POSITIVE TUMOR METASTATIC BREAST CANCER PIK3CA MUTATION