New hope for advanced breast cancer: major trial tests drug combo to keep cancer in check

NCT ID NCT04650581

Ongoing Disease control Sponsor: Canadian Cancer Trials Group Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called ipatasertib to standard fulvestrant therapy can better control advanced breast cancer that has started growing again after initial treatment. It involves about 250 postmenopausal women whose cancer is hormone-sensitive and HER-2 negative. Participants are randomly assigned to receive either the real drug combination or fulvestrant with a placebo pill to compare effectiveness and side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Alfred Hospital

Melbourne, Victoria, 3004, Australia
Algoma District Cancer Program

Sault Ste. Marie, Ontario, P6B 0A8, Canada
Allan Blair Cancer Centre

Regina, Saskatchewan, S4T 7T1, Canada
Auckland City Hospital

Auckland, 1023, New Zealand
BCCA - Cancer Centre for the Southern Interior

Kelowna, British Columbia, V1Y 5L3, Canada
BCCA - Fraser Valley Cancer Centre

Surrey, British Columbia, V3V 1Z2, Canada
BCCA - Vancouver Cancer Centre

Vancouver, British Columbia, V5Z 4E6, Canada
CHA-Hopital Du St-Sacrement

Québec, Quebec, G1S 4L8, Canada
CHUM-Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
Canberra Hospital

Garran, ACT 2605, Australia
Centre Integre de Sante et de Services Sociaux

Greenfield Park, Quebec, J4V 2H1, Canada
Fiona Stanley Hospital

Murdoch, Western Australia, 6150, Australia
Frankston Hospital

Frankston, Victoria, 3199, Australia
Gosford Hospital

Gosford, New South Wales, 2250, Australia
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
Kingston Health Sciences Centre

Kingston, Ontario, K7L 2V7, Canada
Lake Macquarie Private Hospital

Gateshead, New South Wales, 2324, Australia
London Regional Cancer Program

London, Ontario, N6A 5W9, Canada
Macquarie University Hospital

Macquarie University, New South Wales, 2109, Australia
Ottawa Hospital Research Institute

Ottawa, Ontario, K1H 8L6, Canada
QEII Health Sciences Centre

Halifax, Nova Scotia, B3H 1V7, Canada
Regional Health Authority B, Zone 2

Saint John, New Brunswick, E2L 4L2, Canada
Royal Brisbane and Womens Hospital

Herston, 4029, Australia
Royal Victoria Regional Health Centre

Barrie, Ontario, L4M 6M2, Canada
Saskatoon Cancer Centre

Saskatoon, Saskatchewan, S7N 4H4, Canada
Shoalhaven Cancer Care Centre

Nowra, New South Wales, 2541, Australia
Southern Highlands Cancer Centre

Bowral, New South Wales, 2576, Australia
St John of God Bunbury

Bunbury, Western Australia, 6230, Australia
Stronach Regional Health Centre at Southlake

Newmarket, Ontario, L3Y 2P9, Canada
Sunshine Coast University Hospital

Birtinya, Queensland, 4575, Australia
Sunshine Hospital

St Albans, Victoria, 3021, Australia
The Northern Hospital

Epping, Victoria, 3076, Australia
Thunder Bay Regional Health Sciences Centre/

Thunder Bay, Ontario, P7B 6V4, Canada
Toowoomba Hospital

Toowoomba, Queensland, 4350, Australia
University Health Network

Toronto, Ontario, M5G 2M9, Canada
Victorian Breast and Oncology Care

East Melbourne, Victoria, 3002, Australia
Wellington Cancer Centre, Wellington Hospital

Wellington, 2, New Zealand
William Osler Health System

Brampton, Ontario, L6R 3J7, Canada
Windsor Regional Cancer Centre

Windsor, Ontario, N8W 2X3, Canada

Conditions

Explore the condition pages connected to this study.

BREAST CANCER