New breast cancer treatment aims to reduce harsh side effects

NCT ID NCT04893109

Recruiting now Disease control Sponsor: Dana-Farber Cancer Institute Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a newer targeted drug combination (T-DM1 followed by Herceptin Hylecta) causes fewer side effects than the standard treatment (paclitaxel with Herceptin Hylecta) for people with early-stage HER2-positive breast cancer after surgery. About 500 participants will receive one of these year-long treatments and be followed for 5 years. The main goals are to compare side effects and see if both approaches are equally effective at keeping cancer from returning.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Berkshire Medical Center
RECRUITING

Pittsfield, Massachusetts, 01201, United States

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Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States

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Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States

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Dana Farber at South Shore Hospital
RECRUITING

Weymouth, Massachusetts, 02190, United States

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Dana-Farber Brigham Cancer Center - Foxborough
RECRUITING

Foxborough, Massachusetts, 02035, United States

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Dana-Farber Cancer Insitute at Londonderry Hospital
RECRUITING

Londonderry, New Hampshire, 03053, United States

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Dana-Farber Cancer Instiute - Merrimack Valley
RECRUITING

Methuen, Massachusetts, 01844, United States

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Dana-Farber at Milford
RECRUITING

Milford, Massachusetts, 01757, United States

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Dana-Farber at St. Elizabeth's Medical Center
RECRUITING

Brighton, Massachusetts, 02135, United States

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Duke University Medical Center
ACTIVE_NOT_RECRUITING

Durham, North Carolina, 27710, United States
Duke Women's Cancer Care Raleigh
ACTIVE_NOT_RECRUITING

Raleigh, North Carolina, 27710, United States
Eastern Maine Medical Center (Northern Light)
RECRUITING

Brewer, Maine, 04412, United States

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Greco-Hainsworth Centers for Research/Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States

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IU Health North Hospital
ACTIVE_NOT_RECRUITING

Carmel, Indiana, 46032, United States
Indiana University Health Joe & Shelly Schwarz Cancer Center
ACTIVE_NOT_RECRUITING

Carmel, Indiana, 46032, United States
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
ACTIVE_NOT_RECRUITING

Indianapolis, Indiana, 46202, United States
Indiana University Sidney and Lois Eskenazi Hospital
ACTIVE_NOT_RECRUITING

Indianapolis, Indiana, 46202, United States
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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Mass General North Shore Cancer Center
RECRUITING

Danvers, Massachusetts, 01923, United States

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Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02215, United States

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Miami Cancer Institute - Plantation (MCIP)
RECRUITING

Plantation, Florida, 33324, United States

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Miami Cancer Institute/Baptist Hospital of Miami
RECRUITING

Miami, Florida, 33176, United States

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NH Oncology-Hematology, PA - Payson Center for Cancer Care
RECRUITING

Concord, New Hampshire, 03301, United States

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New England Cancer Specialists
RECRUITING

Scarborough, Maine, 04074, United States

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New England Cancer Specialists - Portsmouth
RECRUITING

Portsmouth, New Hampshire, 03801, United States

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New York University Langone Health
RECRUITING

New York, New York, 10016, United States

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New York University Langone Hospital - Long Island
RECRUITING

Mineola, New York, 11501, United States

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New York University Langone Hospital -Brooklyn
RECRUITING

Brooklyn, New York, 11220, United States

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Newton Wellesley Hospital
RECRUITING

Newton, Massachusetts, 02462, United States

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Northwell University
RECRUITING

New York, New York, 10075, United States

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SCRI Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States

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Smilow Cancer Hospital Care center at Derby
RECRUITING

Derby, Connecticut, 06418, United States

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Smilow Cancer Hospital Care center at Fairfield
RECRUITING

Fairfield, Connecticut, 06824, United States

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Smilow Cancer Hospital Care center at Glastonbury
RECRUITING

Glastonbury, Connecticut, 06033, United States

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Smilow Cancer Hospital Care center at Greenwich
RECRUITING

Greenwich, Connecticut, 06830, United States

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Smilow Cancer Hospital Care center at Guilford
RECRUITING

Guilford, Connecticut, 06437, United States

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Smilow Cancer Hospital Care center at Long Ridge
RECRUITING

Long Ridge, Connecticut, 06902, United States

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Smilow Cancer Hospital Care center at North Haven
RECRUITING

North Haven, Connecticut, 06510, United States

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Smilow Cancer Hospital Care center at St. Francis
RECRUITING

Hartford, Connecticut, 06105, United States

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Smilow Cancer Hospital Care center at Torrington
RECRUITING

Torrington, Connecticut, 06790, United States

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Smilow Cancer Hospital Care center at Trumbull
RECRUITING

Trumbull, Connecticut, 06611, United States

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Smilow Cancer Hospital Care center at Waterbury
RECRUITING

Waterbury, Connecticut, 06708, United States

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Smilow Cancer Hospital Care center at Waterford
RECRUITING

Waterford, Connecticut, 06385, United States

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Smilow Cancer Hospital Care center at Westerly
RECRUITING

Westerly, Rhode Island, 02891, United States

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Solinsky Center for Cancer Care (NH Oncology-Hematology, PA)
RECRUITING

Manchester, New Hampshire, 03103, United States

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Stamford Hospital
RECRUITING

Stamford, Connecticut, 06904, United States

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Stefanie Spielman Comprehensive Breast Center
RECRUITING

Columbus, Ohio, 43212, United States

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The University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States

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UCSF Helen Diller Family Comprehensive Cancer Center
RECRUITING

San Francisco, California, 94158, United States

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University of Pennsylvania, Abramson Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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University of Pittsburgh Medical Center Cancer UPMC- Magee Women's Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

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Yale Cancer Center at Yale University School of Medicine
RECRUITING

New Haven, Connecticut, 06520-8028, United States

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Conditions

Explore the condition pages connected to this study.

BREAST CANCER HER2-POSITIVE BREAST CANCER