New breast cancer drug aims for fewer side effects

NCT ID NCT01853748

Completed Disease control Sponsor: Dana-Farber Cancer Institute Source: ClinicalTrials.gov ↗

Summary

This study tested if a newer drug called T-DM1 causes fewer serious side effects than the standard two-drug combination (paclitaxel and trastuzumab) for early-stage HER2-positive breast cancer. It involved 512 women who had recently had breast cancer surgery. The main goals were to compare side effects and see if T-DM1 was as good at keeping cancer from coming back over three years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Arnold Palmer Cancer Center-Greensburg

Greensburg, Pennsylvania, 15601, United States
Arnold Palmer Medical Oncology Oakbrook

Greensburg, Pennsylvania, 15642, United States
Arnold Palmer Medical Oncology-Mt Pleasant

Mount Pleasant, Pennsylvania, 15666, United States
Barnes-Jewish Hospital

St Louis, Missouri, 63110, United States
Baylor College of Medicine-Baylor Clinic

Houston, Texas, 77030, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Dana Farber Cancer Institute at Faulkner Hospital

Boston, Massachusetts, 02130, United States
Dana-Farber Cancer Insitute at Londonderry Hospital

Londonderry, New Hampshire, 03053, United States
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Dana-Farber Cancer Institute at Milford Hospital

Milford, Massachusetts, 01757, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Eastern Maine Medical Center's Cancer Care

Brewer, Maine, 04412, United States
Florida Cancer Specialists

Fort Myers, Florida, 33916, United States
Florida Cancer Specialists

St. Petersburg, Florida, 337054, United States
Georgetown Hospital

Washington D.C., District of Columbia, 20007, United States
Harris County Hospital District-Ben Taub General Hospital

Houston, Texas, 77030, United States
Harris County Hospital District-Smith Clinic

Houston, Texas, 77054, United States
Hartford Healthcare Cancer Institute at The Hospital of Central Connecticut

New Britain, Connecticut, 06050, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Indiana University - Springmill Medical Clinic

Indianapolis, Indiana, 46290, United States
Indiana University - Wishard Hospital

Indianapolis, Indiana, 46202, United States
Indiana University Health - Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Indiana University Health - University Hospital

Indianapolis, Indiana, 46202, United States
Johns Hopkins - Green Spring Station

Lutherville, Maryland, 21093, United States
Johns Hopkins - Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland, 21287, United States
Lehigh Valley Hospital/Lehigh Valley Health Network

Allentown, Pennsylvania, 18103, United States
Lowell General Hospital

Lowell, Massachusetts, 01854, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
MD Anderson Cancer Center

Houston, Texas, 77030, United States
Mass General North Shore Cancer Center

Danvers, Massachusetts, 01923, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Cancer Center Westchester

East White Plains, New York, 10604, United States
Memorial Sloan Kettering Cancer Center-Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Cancer Center-Mercy

Rockville Centre, New York, 11570, United States
Memorial Sloan Kettering Cancer Center-Sleepy Hollow

Sleepy Hollow, New York, 10591, United States
Memorial Sloan Kettering Cancer Center-Suffolk

Commack, New York, 11725, United States
Midstate Medical Center

Meriden, Connecticut, 06451, United States
Mountain States Tumor Institute

Boise, Idaho, 83712, United States
Mountain States Tumor Institute

Fruitland, Idaho, 83619, United States
Mountain States Tumor Institute

Meridian, Idaho, 83642, United States
Mountain States Tumor Institute

Nampa, Idaho, 83686, United States
Mountain States Tumor Institute

Twin Falls, Idaho, 83301, United States
New Hampshire Oncology-Hematology, PA

Concord, New Hampshire, 03301, United States
New Hampshire Oncology-Hematology, PA

Hooksett, New Hampshire, 03106, United States
New Hampshire Oncology-Hematology, PA

Laconia, New Hampshire, 03246, United States
Northwell Health/Monter Cancer Center

Lake Success, New York, 11042, United States
Queens Hospital Center, Comprehensive Cancer Center

Jamaica, New York, 11432, United States
Rex Cancer Center

Raleigh, North Carolina, 27607, United States
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Siteman Cancer Center - South County

St Louis, Missouri, 63129, United States
Siteman Cancer Center - St. Peters

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center - West County

St Louis, Missouri, 63141, United States
Suburban Hospital Cancer Program

Bethesda, Maryland, 20817, United States
Tennessee Oncology/Sarah Cannon Research Institute

Nashville, Tennessee, 37203, United States
The Ohio State University

Columbus, Ohio, 43212, United States
UPMC Cancer Center Jefferson Regional Med Ctr

Jefferson Hills, Pennsylvania, 15025, United States
UPMC Cancer Center St. Clair Hospital

Pittsburgh, Pennsylvania, 15232, United States
UPMC CancerCenters Butler

Butler, Pennsylvania, 16001, United States
UPMC Conemaugh Cancer Center

Johnstown, Pennsylvania, 15905, United States
UPMC East

Monroeville, Pennsylvania, 15146, United States
UPMC Horizon (Greenville)

Greenville, Pennsylvania, 16125, United States
UPMC Horizon (Shenango)

Farrell, Pennsylvania, 16121, United States
UPMC Jameson Cancer Center

New Castle, Pennsylvania, 16105, United States
UPMC McKeesport

McKeesport, Pennsylvania, 15132, United States
UPMC Northwest (Franklin)

Seneca, Pennsylvania, 16346, United States
UPMC Northwest (Oil City)

Seneca, Pennsylvania, 16346, United States
UPMC Passavant

Pittsburgh, Pennsylvania, 15237, United States
UPMC Pinnacle Harrisburg

Harrisburg, Pennsylvania, 17101, United States
UPMC Presbyterian Shadyside

Pittsburgh, Pennsylvania, 15232, United States
UPMC St. Margaret

Pittsburgh, Pennsylvania, 15215, United States
UPMC and the Washington Hospital Center

Washington, Pennsylvania, 15301, United States
UPMC/HVHS Cancer Center, UPMC Beaver

Beaver, Pennsylvania, 15143, United States
Univeristy of Michigan Health System

Ann Arbor, Michigan, 48109, United States
University of Alabama Birmingham

Birmingham, Alabama, 35249, United States
University of California San Francisco

San Francisco, California, 94115, United States
University of Chicago Comprehensive Cancer Center at Silver Cross Hospital

New Lenox, Illinois, 60451, United States
University of Chicago Medical Center for Advanced Care Orland Park

Orland Park, Illinois, 60462, United States
University of North Carolina

Chapel Hill, North Carolina, 27599, United States
University of Washington Seattle Cancer Care Alliance

Seattle, Washington, 98109, United States
Vanderbilt-Ingram Cancer Center

Nashville, Tennessee, 37232, United States
Washington Cancer Institute at Medstar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Washington University, School of Medicine

St Louis, Missouri, 63110, United States
William W Backus Hospital

Norwich, Connecticut, 06360, United States

Conditions

Explore the condition pages connected to this study.

BREAST CANCER