New hope for aggressive breast cancer: drug combo trial shows promise

NCT ID NCT04603183

Summary

This study compared two treatment approaches for people with advanced, aggressive breast cancer that has spread and cannot be removed by surgery. One group received a newer targeted pill (abemaciclib) plus standard hormone therapy. The other group started with a short course of chemotherapy (paclitaxel) before switching to the same pill and hormone therapy. The main goal was to see which approach led to better tumor shrinkage within the first 12 weeks.

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Contacts and locations

Locations

  • Azienda Ospedaliero-Universitaria Cittá de la Salute e della Scienza

    Torino, 10126, Italy

  • Centro Oncoloxico de Galicia

    A Coruña, Coruña, 15009, Spain

  • Complejo Asistencial Universitario De León

    León, Leon, 24073, Spain

  • Complejo Hospitalario de Navarra

    Pamplona, Pamplona/Iruña, 31008, Spain

  • Consorcio Hospital General Universitario de Valencia

    Valencia, 46014, Spain

  • Consorcio Hospitalario Provincial de Castellon

    Castellon, 12002, Spain

  • Fundación Althaia Manresa

    Manresa, Barcelona, 08243, Spain

  • Hospital Arnau de Vilanova

    Valencia, 46015, Spain

  • Hospital Beata María Ana

    Madrid, 28007, Spain

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Fernando da Fonseca

    Amadora, 2720-276, Portugal

  • Hospital General Universitario de Alicante

    Alicante, 03010, Spain

  • Hospital Quiron Salud Dexeus

    Barcelona, Spain

  • Hospital Quironsalud Valencia

    Valencia, 460137, Spain

  • Hospital Quirónsalud Sagrado Corazón

    Seville, 41013, Spain

  • Hospital Ruber Juan Bravo

    Madrid, 28006, Spain

  • Hospital Universitari de Sant Joan de Reus

    Reus, Tarragona, 43204, Spain

  • Hospital Universitario Arnau de Vilanova

    Lleida, 25198, Spain

  • Hospital Universitario Basurto

    Bilbao, 48013, Spain

  • Hospital Universitario Clinico San Carlos

    Madrid, 28040, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hospital Universitario Miguel Servet

    Zaragoza, 50009, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Reina Sofia

    Córdoba, Cordoba, 14004, Spain

  • Hospital Universitario San Cecilio

    Granada, 18016, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, Andalusia, Spain

  • Hospital de Santa Maria - Centro Hospitalar Lisboa Norte

    Lisbon, 1600-190, Portugal

  • Institut Catala D'Oncologia Girona - Hospital Josep Trueta

    Girona, 17007, Spain

  • Instituto Europeo di Oncologia

    Milan, 20141, Italy

  • Ospedale Guglielmo da Saliceto

    Piacenza, 29121, Italy

  • Ospedale San Gerardo

    Monza, 20900, Italy

Conditions

Explore the condition pages connected to this study.