New surgical method could spare breast cancer patients from debilitating arm swelling

NCT ID NCT03927027

Ongoing Disease control Sponsor: Alliance for Clinical Trials in Oncology Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 trial is testing whether a surgical technique called axillary reverse mapping can prevent lymphedema—painful arm swelling—in breast cancer patients having lymph node removal surgery. Researchers are comparing patients who receive the new mapping procedure during surgery to those who don't, tracking arm swelling and cancer recurrence for three years. The goal is to preserve the body's natural drainage system during cancer surgery to improve long-term quality of life.

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Contacts and locations

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Locations

Advocate Christ Medical Center

Oak Lawn, Illinois, 60453-2699, United States
Alta Bates Summit Medical Center - Summit Campus

Oakland, California, 94609, United States
Anne Arundel Medical Center

Annapolis, Maryland, 21401, United States
Ascension Medical Group Southeast Wisconsin - Mayfair Road

Wauwatosa, Wisconsin, 53226, United States
Ascension Southeast Wisconsin Hospital - Elmbrook Campus

Brookfield, Wisconsin, 53045, United States
Asplundh Cancer Pavilion

Willow Grove, Pennsylvania, 19090, United States
Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311, United States
Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233, United States
Aurora West Allis Medical Center

West Allis, Wisconsin, 53227, United States
Baptist MD Anderson Cancer Center

Jacksonville, Florida, 32207, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

Houston, Texas, 77030, United States
Beebe Health Campus

Rehoboth Beach, Delaware, 19971, United States
Beebe South Coastal Health Campus

Frankford, Delaware, 19945, United States
Cancer Institute at Saint Francis Hospital

East Hills, New York, 11548, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Contra Costa Regional Medical Center

Martinez, California, 94553-3156, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Geauga Hospital

Chardon, Ohio, 44024, United States
Geisinger South Wilkes-Barre

Wilkes-Barre, Pennsylvania, 18765, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Good Samaritan Hospital Medical Center

West Islip, New York, 11795, United States
Goshen Center for Cancer Care

Goshen, Indiana, 46526, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038, United States
Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322, United States
Henry Ford Wyandotte Hospital

Wyandotte, Michigan, 48192, United States
Holy Cross Hospital

Fort Lauderdale, Florida, 33308, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MD Anderson League City

League City, Texas, 77573, United States
MD Anderson West Houston

Houston, Texas, 77079, United States
MD Anderson in Sugar Land

Sugar Land, Texas, 77478, United States
MD Anderson in The Woodlands

Conroe, Texas, 77384, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
McLaren Cancer Institute-Bay City

Bay City, Michigan, 48706, United States
Mount Carmel East Hospital

Columbus, Ohio, 43213, United States
Mount Carmel New Albany Surgical Hospital

New Albany, Ohio, 43054, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, 10032, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Orlando Health Cancer Institute

Orlando, Florida, 32806, United States
Parkland Memorial Hospital

Dallas, Texas, 75235, United States
Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, 19104, United States
Pennsylvania Hospital

Philadelphia, Pennsylvania, 19107, United States
Piedmont Fayette Hospital

Fayetteville, Georgia, 30214, United States
Pluta Cancer Center

Rochester, New York, 14623, United States
Robert Wood Johnson University Hospital Somerset

Somerville, New Jersey, 08876, United States
Rush University Medical Center

Chicago, Illinois, 60612, United States
Saint John's Cancer Institute

Santa Monica, California, 90404, United States
Shaw Cancer Center

Edwards, Colorado, 81632, United States
Sidney Kimmel Cancer Center Washington Township

Sewell, New Jersey, 08080, United States
Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
The James Graham Brown Cancer Center at University of Louisville

Louisville, Kentucky, 40202, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UH Seidman Cancer Center at Firelands Regional Medical Center

Sandusky, Ohio, 44870, United States
UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060, United States
UH Seidman Cancer Center at Saint John Medical Center

Westlake, Ohio, 44145, United States
UH Seidman Cancer Center at Southwest General Hospital

Middleburg Heights, Ohio, 44130, United States
UHHS-Chagrin Highlands Medical Center

Beachwood, Ohio, 44122, United States
UHHS-Westlake Medical Center

Westlake, Ohio, 44145, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables

Coral Gables, Florida, 33146, United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach

Deerfield Beach, Florida, 33442, United States
UM Sylvester Comprehensive Cancer Center at Kendall

Miami, Florida, 33176, United States
UM Sylvester Comprehensive Cancer Center at Plantation

Plantation, Florida, 33324, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
UTMB Cancer Center at Victory Lakes

League City, Texas, 77573, United States
UTMB Health Angleton Danbury Campus

Angleton, Texas, 77515, United States
University Hospitals Parma Medical Center

Parma, Ohio, 44129, United States
University Hospitals Portage Medical Center

Ravenna, Ohio, 44266, United States
University Hospitals Sharon Health Center

Wadsworth, Ohio, 44281, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Cincinnati Cancer Center-West Chester

West Chester, Ohio, 45069, United States
University of Florida Health Science Center - Gainesville

Gainesville, Florida, 32610, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kansas Hospital-Indian Creek Campus

Overland Park, Kansas, 66211, United States
University of Kansas Hospital-Westwood Cancer Center

Westwood, Kansas, 66205, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
University of Rochester

Rochester, New York, 14642, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0565, United States
VCU Massey Cancer Center at Stony Point

Richmond, Virginia, 23235, United States
Virginia Commonwealth University/Massey Cancer Center

Richmond, Virginia, 23298, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States
Women and Infants Hospital

Providence, Rhode Island, 02905, United States

Conditions

Explore the condition pages connected to this study.

BREAST CANCER STAGE I BREAST CANCER STAGE II BREAST CANCER STAGE III