Mini tumors in a dish could guide breast cancer therapy

NCT ID NCT06468124

Recruiting now Knowledge-focused Sponsor: King's College London Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is growing miniature versions of breast cancer tumors, called organoids, from samples taken during surgery. Researchers want to see if these lab-grown organoids can predict how well a patient's cancer will respond to treatments like chemotherapy or radiation. If the organoids' sensitivity matches the patient's actual outcome, this approach could one day help doctors personalize cancer therapy. The study involves 20 adults with breast cancer that has spread to the brain or other parts of the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a lab test that helps doctors choose the most effective treatment for each patient's breast cancer metastases.
What could go wrong: This is a very small, early study with only 20 participants. It is designed to gather data, not to test a new treatment, so it may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRAIN METASTASES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm metastatic malignant neoplasm in the brain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASMS

Contacts and locations

Locations

Guy's and St. Thomas NHS Foundation Trust
RECRUITING

London, SE1 9RT, United Kingdom
King's College Hospital NHS Foundation Trust
RECRUITING

London, SE5 9RS, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.