New drug combo aims to shrink tumors before breast cancer surgery

NCT ID NCT06144944

First seen Oct 31, 2025 · Last updated Apr 14, 2026 · Updated 23 times

Summary

This study is testing whether adding a drug called pyrotinib to standard chemotherapy works better than chemotherapy alone for people with a specific type of high-risk, early-stage breast cancer. The goal is to shrink the tumor as much as possible before surgery. About 160 participants will be randomly assigned to receive either the drug combination or just chemotherapy.

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Contacts and locations

Locations

  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    Guangzhou, Guangdong, 510120, China

Conditions

Explore the condition pages connected to this study.