New hope to delay cancer progression in advanced breast cancer

NCT ID NCT02763566

Summary

This study tested whether adding a new drug called abemaciclib to standard hormone therapies helps postmenopausal women with advanced breast cancer live longer without their cancer getting worse. It involved 463 women whose cancer had returned or spread and was fueled by hormones but not by the HER2 protein. The main goal was to see if the combination treatment delayed cancer progression more effectively than standard hormone therapy alone.

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Contacts and locations

Locations

  • Afflilated Hospital of Bengbu Medical College

    Bengbu, Anhui, 233004, China

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa

    Porto Alegre, Rio Grande do Sul, 90110-270, Brazil

  • Christian Medical College Vellore

    Ranipet, Tamil Nadu, 632513, India

  • Clínica de Pesquisa e Centro de Estudos em Ginecologia Oncológica e Mamária LTDA

    São Paulo, 01317-000, Brazil

  • Dr. B. L. Kapur Memorial Hospital

    New Delhi, National Capital Territory of Delhi, 110005, India

  • Eastleigh Breast Care Center

    Pretoria, Gauteng, 0081, South Africa

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200032, China

  • Fujian Provincial Cancer hospital

    Fuzhou, Fujian, 350014, China

  • Fundação Pio XII - Hospital de Câncer de Barretos

    Barretos, São Paulo, 14784-400, Brazil

  • Fuzhou General hospital of Nanjing Military Command

    Fuzhou, Fujian, 350025, China

  • Guangdong Province People's Hospital

    Guangzhou, Guangdong, 510080, China

  • Guangxi Medical University Affiliated Tumor Hospital

    Nanning, Guangxi, 530021, China

  • Harbin Medical University Caner Hospital

    Harbin, Heilongjiang, 150081, China

  • Healthcare Global Enterprises Limited (HCG)

    Bangalore, Karnataka, 560027, India

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450008, China

  • Hospital de Base de Sao Jose do Rio Preto

    São José do Rio Preto, São Paulo, 15091-000, Brazil

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430079, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410013, China

  • Icesp - Instituto Do Câncer Do Estado de São Paulo

    São Paulo, 01246-000, Brazil

  • Jehangir Hospital

    Pune, Maharashtra, 411001, India

  • Jiangsu Cancer Hospital

    Nanjing, Jiangsu, 210009, China

  • Jiangsu Province Hospital

    Nanjing, Jiangsu, 210029, China

  • Jilin Province Tumor Hospital

    Changchun, Jilin, 130012, China

  • Liaoning Cancer Hospital&Institute

    Shenyang, Liaoning, 100042, China

  • M S Ramaiah Medical College Hospitals

    Bangalore, Karnataka, 560054, India

  • Medica Superspecialty Hospital

    Kolkata, West Bengal, 700099, India

  • Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School

    Nanjing, Jiangsu, 210000, China

  • ONCOSITE - Centro de Pesquisa Clinica em Oncologia

    Ijuí, Rio Grande do Sul, 98700 000, Brazil

  • Sandton Oncology Centre

    Johannesburg, 2196, South Africa

  • Shanghai General Hospital

    Shanghai, Shanghai Municipality, 200080, China

  • Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University

    Guangzhou, Guangdong, 510120, China

  • Tata Memorial Hospital

    Mumbai, Maharashtra, 400 012, India

  • The 2nd Affiliated Hospital of Dalian Medical University

    Dalian, Liaoning, 116023, China

  • The Fifth Medical Center of PLA General Hospital

    Beijing, Beijing Municipality, 100071, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shaanxi, 710061, China

  • The Fourth Hospital of Hebei Medical University

    Shijiazhuang, Hebei, 50035, China

  • The Gujarat Cancer & Research Institute (GCRI)

    Ahmedabad, Gujarat, 380016, India

  • The Medical Oncology Centre of Rosebank

    Johannesburg, Gauteng, 2196, South Africa

  • The Second Affiliate Hospital of Zhejiang University School of medicine

    Hangzhou, Zhejiang, 310052, China

  • The first affiliated hospital of China medical university

    Shenyang, Liaoning, 110001, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjin, Tianjin Municipality, China

  • Tongji Hospital Tongji Medical, Science & Technology

    Wuhan, Hubei, 430030, China

  • Wuhan Union Hospital Cancer Center

    Wuhan, Hubei, 430022, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

Conditions

Explore the condition pages connected to this study.