Breast cancer trial seeks better tolerated treatment schedule

NCT ID NCT02630693

Summary

This study compared two different dosing schedules for the drug palbociclib when combined with standard hormone therapy for advanced breast cancer. Researchers wanted to see if a lower daily dose (100 mg every day) would work as well or better than the standard schedule (125 mg for 21 days, then 7 days off) while causing fewer side effects that require treatment breaks. The trial involved 180 women whose breast cancer had progressed despite previous hormone therapy.

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Contacts and locations

Locations

  • Allan Blair Cancer Centre

    Regina, Saskatchewan, S4T 7T1, Canada

  • BCCA - Abbotsford Centre

    Abbotsford, British Columbia, V2S 0C2, Canada

  • BCCA - Fraser Valley Cancer Centre

    Surrey, British Columbia, V3V 1Z2, Canada

  • BCCA - Vancouver Cancer Centre

    Vancouver, British Columbia, V5Z 4E6, Canada

  • CHA-Hopital Du St-Sacrement

    Québec, Quebec, G1S 4L8, Canada

  • CHUM - Hopital Notre-Dame

    Montreal, Quebec, H2L 4M1, Canada

  • Cancer Centre of Southeastern Ontario at Kingston

    Kingston, Ontario, K7L 5P9, Canada

  • Centre hospitalier universitaire de Sherbrooke

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Cross Cancer Institute

    Edmonton, Alberta, T6G 1Z2, Canada

  • Dr. H. Bliss Murphy Cancer Centre

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

  • Hopital du Sacre-Coeur de Montreal

    Montreal, Quebec, H4J 1C5, Canada

  • Juravinski Cancer Centre at Hamilton Health Sciences

    Hamilton, Ontario, L8V 5C2, Canada

  • Lakeridge Health Oshawa

    Oshawa, Ontario, L1G 2B9, Canada

  • Niagara Health System

    St. Catharines, Ontario, L2S 0A9, Canada

  • Ottawa Hospital Research Institute

    Ottawa, Ontario, K1H 8L6, Canada

  • QEII Health Sciences Centre

    Halifax, Nova Scotia, B3H 1V7, Canada

  • Royal Victoria Regional Health Centre

    Barrie, Ontario, L4M 6M2, Canada

  • Stronach Regional Health Centre at Southlake

    Newmarket, Ontario, L3Y 2P9, Canada

  • The Jewish General Hospital

    Montreal, Quebec, H3T 1E2, Canada

  • The Moncton Hospital

    Moncton, New Brunswick, E1C 6Z8, Canada

  • University Health Network

    Toronto, Ontario, M5G 2M9, Canada

  • Windsor Regional Cancer Centre

    Windsor, Ontario, N8W 2X3, Canada

Conditions

Explore the condition pages connected to this study.