New hope for breast cancer patients: trial tests smarter drug combo after standard therapy

NCT ID NCT05760612

First seen Sep 30, 2025 · Last updated May 15, 2026 · Updated 31 times

Summary

This study is for women with a certain type of breast cancer (HER2-positive, hormone receptor-positive) who still have small amounts of cancer after initial treatment. It compares two drug combinations to see which works better at preventing the cancer from coming back. About 300 participants will be randomly assigned to receive either trastuzumab plus neratinib or trastuzumab plus pertuzumab, and researchers will track how long they stay cancer-free.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen University Sun Yat-sen Memorial Hospital

    RECRUITING

    Guangzhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.