New drug duo tested to shrink aggressive breast cancer before surgery

NCT ID NCT05795101

Summary

This study is testing whether a combination of two drugs, trastuzumab deruxtecan and durvalumab, can shrink tumors before surgery in people with stage III inflammatory breast cancer that expresses the HER2 protein. The goal is to see if this treatment can eliminate all detectable cancer in the breast and lymph nodes by the time of surgery. About 63 adults who have not yet received treatment for this specific cancer are needed for the study.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-••••

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.