New hope for advanced breast cancer: testing powerful drug combos

NCT ID NCT04538742

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether combining an existing breast cancer drug (trastuzumab deruxtecan) with other cancer medications is safe and effective for people with advanced HER2-positive breast cancer that has spread. Researchers will enroll 245 patients to find the best doses and see how well these combinations work. The trial includes patients both with and without brain metastases, and some participants will receive these combinations as their first treatment for advanced disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Research Site

Fort Myers, Florida, 33901, United States
Research Site

St. Petersburg, Florida, 33705, United States
Research Site

Commack, New York, 11725, United States
Research Site

Harrison, New York, 10604, United States
Research Site

New York, New York, 10016, United States
Research Site

New York, New York, 10065, United States
Research Site

Columbus, Ohio, 43219, United States
Research Site

Nashville, Tennessee, 37203, United States
Research Site

Fort Worth, Texas, 76104, United States
Research Site

Fairfax, Virginia, 22031, United States
Research Site

Melbourne, 3000, Australia
Research Site

Barretos, 14784-400, Brazil
Research Site

Belo Horizonte, 30150-274, Brazil
Research Site

Natal, 59075-740, Brazil
Research Site

Porto Alegre, 90610-000, Brazil
Research Site

Porto Alegre, 91350-200, Brazil
Research Site

Rio de Janeiro, 20560-120, Brazil
Research Site

São Paulo, 01317-001, Brazil
Research Site

São Paulo, 04029-000, Brazil
Research Site

Sorocaba, 18030-005, Brazil
Research Site

Montreal, Quebec, H2X 0A9, Canada
Research Site

Québec, Quebec, G1S 4L8, Canada
Research Site

Toronto, M5G 2M9, Canada
Research Site

Villejuif, 94805, France
Research Site

München, 81675, Germany
Research Site

Würzburg, 97080, Germany
Research Site

Delhi, 110085, India
Research Site

Gūrgaon, 122001, India
Research Site

Madurai, 625107, India
Research Site

Mumbai, 400012, India
Research Site

Bologna, 40138, Italy
Research Site

Milan, 20141, Italy
Research Site

Naples, 80131, Italy
Research Site

Rome, 168, Italy
Research Site

Bydgoszcz, 85-796, Poland
Research Site

Koszalin, 75-581, Poland
Research Site

Lodz, 90-242, Poland
Research Site

Lublin, 20-090, Poland
Research Site

Moscow, 105229, Russia
Research Site

Moscow, 109240, Russia
Research Site

Moscow, 111123, Russia
Research Site

Moscow, 115478, Russia
Research Site

Moscow, 117997, Russia
Research Site

Moscow, 121205, Russia
Research Site

Moscow, 143423, Russia
Research Site

Saint Petersburg, 195271, Russia
Research Site

Saint Petersburg, 196603, Russia
Research Site

Saint Petersburg, 197758, Russia
Research Site

Busan, 602-739, South Korea
Research Site

Seoul, 02841, South Korea
Research Site

Seoul, 03080, South Korea
Research Site

Seoul, 05505, South Korea
Research Site

Seoul, 06351, South Korea
Research Site

Barcelona, 08003, Spain
Research Site

L'Hospitalet de Llobregat, 08908, Spain
Research Site

Madrid, 28007, Spain
Research Site

Madrid, 28050, Spain
Research Site

Seville, 41013, Spain
Research Site

Hualien City, 970, Taiwan
Research Site

Tainan, 704, Taiwan
Research Site

Taipei, 10048, Taiwan
Research Site

Taipei, 10449, Taiwan
Research Site

Taipei, 11217, Taiwan
Research Site

Taipei, 114, Taiwan
Research Site

Taipei, 235, Taiwan
Research Site

Taoyuan, 333, Taiwan
Research Site

Ankara, 6100, Turkey (Türkiye)
Research Site

Edirne, 22030, Turkey (Türkiye)
Research Site

Istanbul, 34662, Turkey (Türkiye)
Research Site

Istanbul, 34722, Turkey (Türkiye)
Research Site

Izmir, 35100, Turkey (Türkiye)
Research Site

Buckhurst Hill, IG9 5HX, United Kingdom

Conditions

Explore the condition pages connected to this study.

METASTATIC BREAST CANCER