New study tests which chemo combo works best for common breast cancers
NCT ID NCT04193059
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial compares two chemotherapy regimens for women with non-triple negative breast cancer after surgery. One group gets epirubicin plus cyclophosphamide followed by docetaxel (EC-T), the other gets paclitaxel plus carboplatin (PCb). The study includes 1560 participants and tracks how long they stay cancer-free. It also looks at side effects and overall survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- chemotherapy drugs (epirubicin, cyclophosphamide, docetaxel, paclitaxel, carboplatin, and trastuzumab)
- What this could lead to
- If successful, this could show that a carboplatin-based regimen works as well as or better than standard anthracycline-based chemo for certain breast cancer types, potentially reducing side effects.
- What could go wrong
- This is a single-center trial, so results may not apply broadly. Chemotherapy has well-known side effects like fatigue, nausea, and increased infection risk. The study is not testing a new drug, just comparing existing options.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cancer Hospital Affiliated to Fudan University
Shanghai, Shanghai Municipality, 200032, China
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