New hope for tough brain cancers: experimental combo therapy enters human testing
NCT ID NCT07243470
Summary
This trial is testing whether adding a new drug called tarlatamab to a standard chemotherapy (temozolomide) is safe and can help control aggressive brain tumors. It will enroll about 70 teenagers and adults whose tumors have a specific marker (DLL3) and have stopped responding to standard treatments. The study first finds the safest dose, then checks if the combination can shrink or stabilize the tumors.
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Contacts and locations
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Study contacts
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Contact
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Locations
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CHU de Bordeaux
NOT_YET_RECRUITINGBordeaux, 33000, France
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Centre Léon Bérard
RECRUITINGLyon, 69373, France
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Centre Oscar Lambret
NOT_YET_RECRUITINGLille, 59000, France
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Hôpital Neurologique Pierre Wertheimer
NOT_YET_RECRUITINGBron, 69677, France
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Hôpital Saint-André
NOT_YET_RECRUITINGBordeaux, 33075, France
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Hôpital Universitaire d'Angers
NOT_YET_RECRUITINGAngers, 49933, France
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Hôpital de la Timone
NOT_YET_RECRUITINGMarseille, 13005, France
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Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix
NOT_YET_RECRUITINGParis, 75013, France
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Contact
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IUCT - Claudius Regaud
NOT_YET_RECRUITINGToulouse, 31100, France
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Institut Gustave Roussy
NOT_YET_RECRUITINGVillejuif, 94085, France
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Institut de Cancérologie de l'Ouest
NOT_YET_RECRUITINGAngers, 49055, France
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Conditions
Explore the condition pages connected to this study.