Could a leukemia drug help fight brain tumors? new study aims to find out

NCT ID NCT07039760

First seen Jan 11, 2026 · Last updated May 22, 2026 · Updated 21 times

Summary

This early-phase study tests whether the drug asciminib, approved for leukemia, can reach brain tumors in children and young adults (ages 6-25) with recurrent or progressive brain tumors. Researchers will also see if adding sildenafil helps more drug enter the tumor. The goal is to measure drug levels in tumor tissue and check safety, not yet to cure the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine/St. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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