Brain training plus exercise may slow memory loss, early study suggests

NCT ID NCT05948930

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining brain training with aerobic exercise for 12 weeks can improve brain function in people with mild cognitive impairment (MCI), a condition that can lead to dementia. Researchers will measure changes in brain structure, blood flow, and thinking skills in 90 adults aged 50-80. The goal is to gather data for a larger future trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If it works, this could point toward a non-drug approach to slow cognitive decline in people with mild cognitive impairment.
What could go wrong
This is a small, early-stage pilot study (90 people) focused on measuring brain changes, not proving clinical benefit. Results may not lead to a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Maryland Baltimore

    RECRUITING

    Baltimore, Maryland, 21201, United States

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Other studies related to the condition(s) this trial covers.