Brain training plus exercise may slow memory loss, early study suggests

NCT ID NCT05948930

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study tests whether combining brain training with aerobic exercise for 12 weeks can improve brain function in people with mild cognitive impairment (MCI), a condition that can lead to dementia. Researchers will measure changes in brain structure, blood flow, and thinking skills in 90 adults aged 50-80. The goal is to gather data for a larger future trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Maryland Baltimore

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If it works, this could point toward a non-drug approach to slow cognitive decline in people with mild cognitive impairment.

What could go wrong

This is a small, early-stage pilot study (90 people) focused on measuring brain changes, not proving clinical benefit. Results may not lead to a treatment.

Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.