Could rapid brain zaps sharpen thinking in Parkinson's?
NCT ID NCT07701785
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study tests whether a short, high-dose course of non-invasive brain stimulation called intermittent theta burst stimulation (iTBS) can safely improve mild cognitive impairment in people with Parkinson's disease. Thirty participants will receive 30 sessions of stimulation over three days, targeting a brain region linked to attention. The goal is to see if this approach is feasible, tolerable, and promising enough for larger trials.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- accelerated intermittent theta-burst stimulation (iTBS) delivered via transcranial magnetic stimulation (TMS) to the right superior parietal lobule
- What this could lead to
- If it works, this could point toward a non-invasive, short-term treatment for cognitive decline in Parkinson's disease.
- What could go wrong
- This is a small, early feasibility study with only 30 participants and no control group, so results may not be conclusive or generalizable. The treatment may cause temporary side effects like headache or scalp irritation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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