Zapping the Brain's fear center may lift depression fast

NCT ID NCT07059143

First seen May 13, 2026 ยท Last updated May 13, 2026

Summary

This study tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (TIS) aimed at the right amygdala to quickly reduce depressive symptoms. Fifty adults with major depressive disorder will receive either real or sham stimulation over six weeks. Researchers will measure changes in depression severity, thinking skills, and daily function to see if the treatment is safe and effective.

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Contacts and locations

Locations

  • Anding Hospital (Mental Health Center of Tianjin Medical University)

    Tianjin, China

  • Ruijin Hospital

    Shanghai, China

  • The Affiliated Brain Hospital Of Guangzhou Medical University

    Guangdong, China

Conditions

Explore the condition pages connected to this study.