Zapping the brain to heal after concussion: new trial tests two non-invasive techniques

NCT ID NCT05236010

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests whether combining cognitive training with brain stimulation (rTMS or tDCS) can improve thinking skills in veterans who have persistent symptoms after mild traumatic brain injury. Participants will receive 16 sessions of training with either real or sham stimulation, and their cognitive function, symptoms, and quality of life will be measured before and after treatment, with follow-ups at 3 and 6 months. The goal is to see if personalized brain stimulation can enhance recovery and guide a larger future trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Minneapolis Veterans Affairs Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55417, United States

    Contact Email: •••••@•••••

  • New Mexico Veterans Affairs Health Care System

    RECRUITING

    Albuquerque, New Mexico, 87108, United States

    Contact Email: •••••@•••••

  • The Mind Research Network

    ACTIVE_NOT_RECRUITING

    Albuquerque, New Mexico, 87106, United States

  • The University of Minnesota

    ACTIVE_NOT_RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • The University of New Mexico

    ACTIVE_NOT_RECRUITING

    Albuquerque, New Mexico, 87106, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rTMS (transcranial magnetic stimulation) and HD-tDCS (transcranial direct current stimulation)

What this could lead to

If it works, this could point toward a non-invasive, personalized treatment to improve cognitive function and quality of life in people with persistent symptoms after mild traumatic brain injury.

What could go wrong

This is a Phase II trial with a relatively small sample (108 participants), so results may not apply to everyone. The treatments are experimental for this condition, and the study is still recruiting, so outcomes are uncertain.

Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.