Zapping the brain to heal after concussion: new trial tests two non-invasive techniques

NCT ID NCT05236010

Recruiting now Disease control Sponsor: University of New Mexico Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study tests whether combining cognitive training with brain stimulation (rTMS or tDCS) can improve thinking skills in veterans who have persistent symptoms after mild traumatic brain injury. Participants will receive 16 sessions of training with either real or sham stimulation, and their cognitive function, symptoms, and quality of life will be measured before and after treatment, with follow-ups at 3 and 6 months. The goal is to see if personalized brain stimulation can enhance recovery and guide a larger future trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: rTMS (transcranial magnetic stimulation) and HD-tDCS (transcranial direct current stimulation)
What this could lead to: If it works, this could point toward a non-invasive, personalized treatment to improve cognitive function and quality of life in people with persistent symptoms after mild traumatic brain injury.
What could go wrong: This is a Phase II trial with a relatively small sample (108 participants), so results may not apply to everyone. The treatments are experimental for this condition, and the study is still recruiting, so outcomes are uncertain.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

Minneapolis Veterans Affairs Medical Center
RECRUITING

Minneapolis, Minnesota, 55417, United States
New Mexico Veterans Affairs Health Care System
RECRUITING

Albuquerque, New Mexico, 87108, United States
The Mind Research Network
ACTIVE_NOT_RECRUITING

Albuquerque, New Mexico, 87106, United States
The University of Minnesota
ACTIVE_NOT_RECRUITING

Minneapolis, Minnesota, 55455, United States
The University of New Mexico
ACTIVE_NOT_RECRUITING

Albuquerque, New Mexico, 87106, United States

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