Brain implant shows promise for Hard-to-Treat seizures in rare epilepsy

NCT ID NCT05339126

Ongoing Disease control Sponsor: NeuroPace Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a brain-responsive neurostimulation system in 24 people aged 12 and older with Lennox-Gastaut syndrome whose seizures are not controlled by medication. The device detects and responds to seizure activity in the brain to reduce drop seizures. The goal is to see if it is safe and effective enough to plan a larger study.

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Conditions

The condition(s) this trial relates to.

epilepsy generalized epilepsy Lennox-Gastaut syndrome visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY LENNOX GASTAUT SYNDROME LENNOX-GASTAUT SYNDROME, INTRACTABLE SEIZURES SEIZURES, GENERALIZED

Contacts and locations

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Locations

Emory University

Atlanta, Georgia, 30322, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mount Sinai Hospital

New York, New York, 10029, United States
NYU Langone Medical Center

New York, New York, 10016, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of California, San Francisco

San Francisco, California, 94143, United States