Timing of brain radiation may change outcomes for cancer patients

NCT ID NCT05545007

First seen May 03, 2026 · Last updated May 12, 2026 · Updated 3 times

Summary

This study tests whether giving focused radiation before surgery for large brain tumors (over 2.1 cm) works better than giving it after surgery. About 146 adults with cancer that has spread to the brain will be randomly assigned to one of the two timing groups. The goal is to see which approach reduces the chance of cancer spreading to the lining of the brain and improves local control.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AOU Sant'Andrea

    RECRUITING

    Rome, Rome, 00189, Italy

    Contact Email: •••••@•••••

    Contact

  • AOUC Azienda Ospedaliero-Universitaria Careggi

    RECRUITING

    Florence, Florence, 50134, Italy

    Contact Email: •••••@•••••

    Contact

  • ASST Spedali Civili di Brescia

    RECRUITING

    Brescia, Brescia, 25123, Italy

    Contact Email: •••••@•••••

    Contact

  • Azienda Ospedaliera Santa Maria di Terni

    RECRUITING

    Terni, Terni, 05100, Italy

    Contact

    Contact Email: •••••@•••••

  • Fondazione IRCCS Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, Milan, 20133, Italy

    Contact Email: •••••@•••••

    Contact

  • Fondazione Policlinico Universitario Agostino Gemelli

    RECRUITING

    Rome, Rome, 00168, Italy

    Contact Email: •••••@•••••

    Contact

  • IRCCS Istituto Clinico Humanitas

    RECRUITING

    Rozzano, Milano, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ospedale del Mare

    RECRUITING

    Naples, Naples, 80147, Italy

    Contact Email: •••••@•••••

    Contact

  • Policlinico Umberto I

    ACTIVE_NOT_RECRUITING

    Rome, Rome, 00161, Italy

Conditions

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