Scientists map brain tumor genetics using blood and spinal fluid

NCT ID NCT05848050

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examined genetic and epigenetic changes in brain metastases from solid cancers. Researchers collected tumor tissue, blood, and spinal fluid from 21 patients during surgery to compare molecular profiles. The goal was to see if liquid biopsies could reliably reflect the genetic makeup of brain metastases, potentially reducing the need for invasive brain surgery in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could improve how doctors detect and treat brain metastases by using blood or spinal fluid tests instead of surgery.
What could go wrong
This was a small, completed study with only 21 participants, so results may not apply to all patients. It was designed to gather knowledge, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Privé Clairval

    Marseille, 13009, France

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