Promising brain metastasis combo trial halted after just one patient

NCT ID NCT05553522

First seen Jan 04, 2026 · Last updated May 08, 2026 · Updated 18 times

Summary

This study aimed to see if combining three drugs (tucatinib, trastuzumab, capecitabine) with precise radiation (SRS) could safely control brain tumors from HER2+ breast cancer. Only one person enrolled before the trial was stopped early. The main goal was to find safe doses and watch for side effects.

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Contacts and locations

Locations

  • Miami Cancer Institute at Baptist Health, Inc.

    Miami, Florida, 33176, United States

Conditions

Explore the condition pages connected to this study.