New scan reveals hidden inflammation in heavy drinkers
NCT ID NCT05885594
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study is testing a new PET scan tracer called [18F]NOS to see if it can detect inflammation in the brain and body of people with alcohol use disorder (AUD). Researchers will compare up to 60 people with AUD and up to 30 healthy volunteers. Each person gets one PET/CT scan. The goal is to learn more about how inflammation relates to AUD, not to treat the condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
[18F]NOS (a radioactive tracer for PET scans)
What this could lead to
If successful, this could help researchers understand how inflammation relates to alcohol use disorder, potentially pointing toward new treatment targets.
What could go wrong
This is a very early, small study (only 4 participants planned) that is not testing a treatment. The tracer is investigational and may not show clear differences between groups.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States