Brain waves under the spotlight: a new clue to cyclic vomiting?

NCT ID NCT05256160

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This study uses a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) to compare brain activity in people with cyclic vomiting syndrome (CVS) and healthy volunteers. The goal is to see if there are differences in cortical excitability—how easily the brain's motor cortex responds to stimulation. Researchers will measure brain responses and heart rate variability to explore potential underlying mechanisms of CVS.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcranial magnetic stimulation (TMS) paired-pulse assessment
What this could lead to
If differences are found, it could point toward new ways to understand or treat cyclic vomiting syndrome.
What could go wrong
This is an exploratory study, so it may not find clear differences, and results may not lead to treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CYCLIC VOMITING SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cyclic vomiting syndrome Familial cyclic vomiting syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.