Ear nerve stimulator could tame Kids' vomiting episodes

NCT ID NCT07465614

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a small device worn on the ear that stimulates the vagus nerve, which helps control nausea and vomiting. Researchers want to see if it can make cyclic vomiting episodes less frequent, shorter, and less severe in 120 children. Half the kids will get an active device, and half will get a sham (fake) device to see if the real one works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

percutaneous electrical nerve field stimulation (PENFS) device

What this could lead to

If it works, this could offer a safe, non-drug option to reduce the frequency and severity of vomiting episodes in children with cyclic vomiting syndrome.

What could go wrong

This is an early-stage trial with only 120 participants, and the sham control means the real benefit may be small. The device requires weekly wear and may not work for all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cyclic vomiting syndrome Familial cyclic vomiting syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••