Stanford tests Brain-Targeting drug for depression relief

NCT ID NCT06408246

Summary

This study aims to understand if adding the medication guanfacine to a standard antidepressant (sertraline) can improve brain network function and help reduce depression symptoms, particularly for people who also experience thinking and concentration problems. Researchers will enroll 162 adults aged 18-60 with depression and track their symptoms, brain activity via MRI scans, and daily functioning over an 8-week treatment period. Participants will be randomly assigned to receive either guanfacine or a placebo, in addition to sertraline, to compare the effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford Psychiatry and Behavioral Sciences Department

    RECRUITING

    Palo Alto, California, 94305, United States

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60607, United States

    Contact

    Contact

Conditions

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