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Mind-Controlled rehab: could brain signals restore hand movement after stroke?

NCT ID NCT07784920

Disease control Sponsor: National University Hospital, Singapore Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time

Summary

This trial tests whether a brain-computer interface called Lifescapes can help stroke survivors with severe hand paralysis improve arm and hand function. The system reads brain signals during imagined movements and pairs them with electrical stimulation and robotic assistance to encourage recovery. The study involves 32 adults who had a stroke 8 weeks to 5 years ago and have moderate to severe arm impairment. Participants will complete 16 training sessions with gradually reduced therapist supervision, and their progress will be tracked for up to 3 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lifescapes, an EEG-based brain-computer interface neurofeedback system that combines motor imagery, biofeedback, electrical stimulation, and robotic assistance
What this could lead to
If effective, this approach could offer a more accessible, less therapist-intensive rehabilitation option to help stroke survivors regain hand function.
What could go wrong
This is a small early-stage trial, and results may not generalize. The therapy requires active participation and may not benefit everyone; there is also a risk of seizures or discomfort from electrical stimulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 21-80 years old; 2. First-ever or recurrent ischemic or haemorrhagic stroke; 3. Stroke onset between 8 weeks and 5 years prior to enrolment; 4. Moderate to severe unilateral upper-limb motor impairment following stroke, defined as a baseline upper-extremity Fugal-Meyer Assessment (FMA-UE) score \<47, and Manual Muscle Testing (MMT) of finger extensor ≤2; 5. Being able to provide informed consent, understand and follow verbal instructions. 6. Having sufficient visual acuity to scan full computer screen. Exclusion Criteria: 1. Pregnant or breastfeeding women; 2. Bilateral stroke; 3. Modified Ashworth Scale (MAS) of finger flexors \>2; 4. Use of a pacemaker or of other implanted stimulators; 5. History of seizures within 90 days before enrolment; 6. Impossible to record EEG because of skin status or skull deformity; 7. Sensorimotor disturbance due to other causes other than stroke; 8. Medically unstable or uncontrolled conditions that may compromise safety or the ability to complete scheduled visits.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Alexandra Hospital

    Singapore, Singapore

  • National University Hospital

    Singapore, Singapore

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