Scientists probe Brain's defense against cancer drug

NCT ID NCT05892068

Summary

This study aims to understand how the cancer drug tucatinib reaches brain tumors in patients whose breast cancer has spread to the brain. Researchers will examine tumor tissue from 9 patients who are already scheduled for brain surgery to see how the drug is absorbed and why some tumors become resistant to treatment. The goal is to gather knowledge that could help improve future therapies for brain metastases.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.