New drug duo tested in fight against recurrent brain cancer
NCT ID NCT05484622
Summary
This early-stage study is testing the safety and initial effects of combining two drugs, vorasidenib and pembrolizumab, in adults with a recurrent or worsening type of brain tumor called glioma. The goal is to see if this combination can help control the cancer by boosting the immune system's attack on the tumor. Participants will receive the drugs before and after planned surgery to remove their tumor.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Dana-Farber Cancer Institute (Site: 840139)
Boston, Massachusetts, 02215, United States
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Duke University (Site: 840110)
Durham, North Carolina, 27705, United States
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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MD Anderson Cancer Center (Site: 840102)
Houston, Texas, 77030, United States
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Massachusetts General Hospital (Site: 840104)
Boston, Massachusetts, 02114, United States
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Mayo Clinic Florida
Cleveland, Ohio, 44195, United States
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Memorial Sloan Kettering Cancer Center (Site: 840117)
New York, New York, 10017, United States
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Northwestern University (Site: 840123)
Chicago, Illinois, 60045, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35249, United States
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University of California, Los Angeles (Site: 840113)
Los Angeles, California, 90095, United States
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University of California, San Francisco (Site: 840149)
San Francisco, California, 94013, United States
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University of Colorado
Aurora, Colorado, 80045, United States
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University of Miami (Site: 840129)
Miami, Florida, 33136, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Pennsylvania Health System
Philadelphia, Pennsylvania, 19104, United States
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University of Utah, Huntsman Cancer Center
Salt Lake City, Utah, 84112, United States
Conditions
Explore the condition pages connected to this study.