Brain blood flow secrets revealed in new MRI study
NCT ID NCT06629090
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 37 times
Summary
This study looks at how the brain manages blood flow when blood pressure drops or carbon dioxide levels rise. Healthy adults aged 20-40 will undergo MRI scans while performing breathing exercises and a simulated postural change. Some will receive a single dose of prazosin, a drug that lowers blood pressure, to see how it affects brain blood flow. The goal is to better understand the brain's response to reduced blood supply.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Wisconsin
RECRUITINGMadison, Wisconsin, 53705, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prazosin
What this could lead to
If successful, this could help understand how the brain regulates blood flow, potentially guiding future treatments for conditions like fainting or stroke.
What could go wrong
This is a small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world conditions, and prazosin may cause dizziness or low blood pressure.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.