New mesh device could seal brain aneurysms, avoid surgery

NCT ID NCT06872684

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a new device called the Surpass Elite with Guardian Flow Diverter for treating brain aneurysms that haven't ruptured. The device is a small mesh tube placed inside the artery to redirect blood flow and seal the aneurysm. About 183 adults aged 18-80 with specific types of aneurysms will be enrolled. The study will check if the device safely blocks the aneurysm and prevents strokes over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Surpass Elite with Guardian Flow Diverter System (a mesh tube placed inside the artery to redirect blood flow away from the aneurysm)

What this could lead to

If successful, this device could offer a safer, less invasive way to treat brain aneurysms and prevent them from rupturing.

What could go wrong

This is a single-arm trial without a comparison group, so results may be less definitive. Risks include stroke or incomplete aneurysm closure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aneurysm brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Carondelet St. Joseph's Hospital

    RECRUITING

    Tucson, Arizona, 85711, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Lahey Hospital and Medical Center

    RECRUITING

    Burlington, Massachusetts, 01803, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lyerly Neurosurgery, an Affiliate of Baptist

    RECRUITING

    Jacksonville, Florida, 32207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mount Sinai Health System

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stanford University School of Medicine

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stony Brook University Hospital

    RECRUITING

    Stony Brook, New York, 11794, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California Davis Health

    RECRUITING

    Davis, California, 95616, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••