New gout pill BR2251 enters Mid-Stage trial

NCT ID NCT07498647

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This Phase 2 trial tests BR2251, a new daily tablet, in 160 adults with gout and high uric acid. Participants receive one of three doses of BR2251 or the standard drug febuxostat for 12 weeks. The goal is to see which dose best lowers uric acid levels and reduces gout flare-ups.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
BR2251 tablets
What this could lead to
If successful, BR2251 could offer a new daily pill option to lower uric acid and reduce gout attacks.
What could go wrong
This is an early Phase 2 dose-finding study with only 160 participants. It may not show clear benefit or could have side effects not yet seen.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gout Hyperuricemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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Other studies related to the condition(s) this trial covers.